The Emperor of All Maladies

The Emperor of All Maladies pdf epub mobi txt 电子书 下载 2025

Siddhartha Mukherjee is a cancer physician and researcher. He is an assistant professor of medicine at Columbia University and a staff cancer physician at the CU/NYU Presbytarian Hospital. A former Rhodes scholar, he graduated from Stanford University, University of Oxford (where he received a PhD studying cancer-causing viruses) and from Harvard Medical School. His laboratory focuses on discovering new cancer drugs using innovative biological methods. Mukherjee trained in cancer medicine at the Dana Farber Cancer Institute of Harvard Medical School and was on the staff at the Massachusetts General Hospital. He has published articles and commentary in such journals as Nature, New England Journal of Medicine, Neuron and the Journal of Clinical Investigation and in publications such as the New York Times and the New Republic. His work was nominated for Best American Science Writing, 2000 (edited by James Gleick). He lives in Boston and New York with his wife, Sarah Sze, an artist, and with his daughter, Leela.

出版者:Scribner
作者:Siddhartha Mukherjee
出品人:
页数:592
译者:
出版时间:2010-11-16
价格:USD 30.00
装帧:Hardcover
isbn号码:9781439107959
丛书系列:
图书标签:
  • 科普 
  • 癌症 
  • 医学 
  • 普利策奖 
  • 科学 
  • 生命 
  • cancer 
  • science 
  •  
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Starred Review. Mukherjee's debut book is a sweeping epic of obsession, brilliant researchers, dramatic new treatments, euphoric success and tragic failure, and the relentless battle by scientists and patients alike against an equally relentless, wily, and elusive enemy. From the first chemotherapy developed from textile dyes to the possibilities emerging from our understanding of cancer cells, Mukherjee shapes a massive amount of history into a coherent story with a roller-coaster trajectory: the discovery of a new treatment--surgery, radiation, chemotherapy--followed by the notion that if a little is good, more must be better, ending in disfiguring radical mastectomy and multidrug chemo so toxic the treatment ended up being almost worse than the disease. The first part of the book is driven by the obsession of Sidney Farber and philanthropist Mary Lasker to find a unitary cure for all cancers. (Farber developed the first successful chemotherapy for childhood leukemia.) The last and most exciting part is driven by the race of brilliant, maverick scientists to understand how cells become cancerous. Each new discovery was small, but as Mukherjee, a Columbia professor of medicine, writes, "Incremental advances can add up to transformative changes." Mukherjee's formidable intelligence and compassion produce a stunning account of the effort to disrobe the "emperor of maladies." (Nov.) (c)

Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved.

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1、“我们相信上帝,但其他人必须用数据说话。。”ipad版p250 2、叶酸抗结剂治疗白血病的故事。。 3、p253,医生目的不是挽救特定人,而是挽救所有人的生命。 4、苏珊桑塔格,疾病的隐喻 5、p263,狮子,狗,人类是仅知的会发生前列腺癌的动物。p265,化学阉割。 6、p285,再次...  

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这是我迄今为止读过最好的科普书。 毫 无疑问,这是一本工程浩大的经典,一本详实严谨的科学著作,同时,它也是一本史诗般的传记。如果说写作的对象在一定程度上决定写作的结果,那这本书的主题 ——被作者称为万疾之王的癌症,在我看来,应该是长长的人类疾病名单中(其实不...  

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1、“我们相信上帝,但其他人必须用数据说话。。”ipad版p250 2、叶酸抗结剂治疗白血病的故事。。 3、p253,医生目的不是挽救特定人,而是挽救所有人的生命。 4、苏珊桑塔格,疾病的隐喻 5、p263,狮子,狗,人类是仅知的会发生前列腺癌的动物。p265,化学阉割。 6、p285,再次...  

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癌症源于我们自身的一些负责调节细胞生长的基础基因的突变。而这种突变基因导致的癌细胞有时会展现出永不停止的分裂。在合适的环境下癌细胞可以一直分裂下去,没有衰老的痕迹,这透露出永生的意味。而这种带着永生意味的分裂却会摧毁我们的身体,带来无可避免的死亡。 这真是...  

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用户评价

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这个作者竟然不是native speaker!!! 不过他的句子确实是异常工整啊!!膜拜 但书的最后还是比较啰嗦。。

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这是一本癌症的传记,这个困扰了人类几千年的疾病。作者是个医生,专业知识扎实,文字又好,功课也做得足。虽然书并不短,但是用四百多页深入浅出的把癌症几千年的历史和近来几百年地医治和研究历讲的生动有力也不是易事。

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语言很elegant,内容很充实,病人的故事很煽情。有几个章节有点拖拉。从cytotoxic drugs到antibody那段记得比较清楚。当年的genentech还是很牛的,一片校园风。

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Fantastic account of the struggle against a diabolical enemy borne out of our own body..

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这个作者竟然不是native speaker!!! 不过他的句子确实是异常工整啊!!膜拜 但书的最后还是比较啰嗦。。

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