图书标签: 病毒学 小RNA病毒科 学术专著 ASM 2010
发表于2024-11-08
The Picornaviruses pdf epub mobi txt 电子书 下载 2024
Picornaviruses afflict the animal kingdom with a wide range of maladies, notably the common cold, encephalitis, hepatitis, meningitis, and polio in humans and the economically devastating foot-and-mouth disease in animals. With contributions from leading experts from around the world, this volume examines the most current breakthroughs as well as the challenges that lie ahead in picornavirus research. Based on the most recent basic and clinical research findings, The Picornaviruses encapsulates our current knowledge of the molecular biology, evolution, and pathogenesis of this large family of viruses. In addition, it examines the diseases that these viruses cause and the latest vaccines and antiviral drugs to prevent and control those diseases.
The first eleven chapters explore the structural and mechanistic bases of picornavirus replication, highlighting new insights about the host cell interactions needed for virus growth. The next six chapters illustrate how the regular occurrence of mutations, typical of viruses with RNA as genetic material, generates the quasispecies dynamics that underlie viral fitness. Together with more drastic recombination events, the book shows how this error-prone RNA replication may have generated the variety of viruses embodied in the different picornavirus genera. The final twelve chapters focus on picornaviruses that cause disease, examining pathogenicity and innate and acquired immune responses against infection as well as the latest vaccine and antiviral drug strategies.
Synthesizing the latest developments in the study of picornaviruses, the book underscores our growing understanding of the close connections among picornavirus biology, diversity, evolution, and disease. Moreover, it serves as a springboard for developing new approaches to understanding this important family of viruses as well as preventing and treating picornaviral diseases.
Hardcover, 493 pages, full-color insert, illustrations, index.
Vadim I. Agol
Institute of Poliomyelitis and Viral Encephalitides, Russian Academy of Medical Sciences, Kievskoye Shosse 27 km., Moscow Region 142782, Russia
Rubén Agudo
Centro de Biología Molecular Severo Ochoa, CSIC-UAM, C/Nicolás Cabrera 1, Cantoblanco, Universidad Autónoma de Madrid, Madrid 28049, Spain
Raul Andino
Mission Bay Genentech Hall, Microbiology and Immunology, University of California, San Francisco, 600 16th Street, Room S572E, Box 2280, San Francisco, CA 94143-2280
Armando Arias
Centro de Biología Molecular Severo Ochoa, CSIC-UAM, C/Nicolás Cabrera 1, Cantoblanco, Universidad Autónoma de Madrid, Madrid 28049, Spain
George Belov
Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Room 126, Rockville, MD 20852
Jeffrey M. Bergelson
Division of Infectious Diseases, Abramson 1202, Children’s Hospital of Philadelphia, 3615 Civic Center Boulevard, Philadelphia, PA 19104
Albert Bosch
Department of Microbiology, University of Barcelona, Ave. Diagonal 645, Barcelona 08028, Spain
Mihnea Bostina
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115
Nora M. Chapman
Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68195-6495
Konstantin Chumakov
Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, HFM-470, Rockville, MD 20852
Florence Colbère-Garapin
Biologie des Virus Enteriques, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris cedex 15, and INSERM U994 Paris, France
Teresa de los Santos
Plum Island Animal Disease Center, North Atlantic Area, Agricultural Research Service, U.S. Department of Agriculture, P.O. Box 848, Greenport, NY 11944
Armando M. De Palma
Laboratory of Virology and Chemotherapy, Department of Microbiology and Immunology, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium
Esteban Domingo
Centro de Biología Molecular Severo Ochoa CSIC-UAM, C/Nicolás Cabrera 1, Cantoblanco, Universidad Autónoma de Madrid, Madrid 28049, Spain
Jonathan D. Dougherty
Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030
Ellie Ehrenfeld
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-8011
Cristina Escarmís
Centro de Biología Molecular Severo Ochoa CSIC-UAM, C/Nicolás Cabrera 1, Cantoblanco, Universidad Autónoma de Madrid, Madrid 28049, Spain
Zongdi Feng
Division of Infectious Diseases, Department of Medicine, and the Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295
Cristina Ferrer-Orta
Institut de Biología Molecular de Barcelona, Parc Científic de Barcelona, Baldiri i Reixac 10, 08028 Barcelona, Spain
David J. Filman
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115
Elizabeth E. Fry
Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford OX3 7BN, United Kingdom
Robert S. Fujinami
Department of Pathology, University of Utah School of Medicine, 30 North 1900 East, Salt Lake City, UT 84132
Alexander E. Gorbalenya
Department of Medical Microbiology, Leiden University Medical Center, Postzone E4-P, P.O. Box 9600, NL-2300 RC Leiden, The Netherlands
Marvin J. Grubman
Plum Island Animal Disease Center, North Atlantic Area, Agricultural Research Service, U.S. Department of Agriculture, P.O. Box 848, Greenport, NY 11944
Kurt E. Gustin
Department of Basic Medical Sciences, University of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, AZ 85004
Marc B. Hershenson
Department of Pediatrics and Communicable Diseases, C. S. Mott Children’s Hospital, University of Michigan Medical School, Ann Arbor, MI 48109
James M. Hogle
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115
Tapani Hovi
National Institute for Health and Welfare (THL) P.O. Box 30 FI-00271 Helsinki, Finland
Christopher C. Kemball
Department of Immunology and Microbial Science SP30-2110, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037
Olen Kew
Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333
Andrew M. Q. King
Institute for Animal Health, Pirbright Laboratory, Pirbright, Woking, Surrey GU24 0NF, United Kingdom
Karla Kirkegaard
Department of Microbiology and Immunology, Fairchild Science Building D309A, Stanford University School of Medicine, Stanford, CA 94305-5402
Nick J. Knowles
Institute for Animal Health, Pirbright Laboratory, Pirbright, Woking, Surrey GU24 0NF, United Kingdom
Satoshi Koike
Neurovirology Project, Tokyo Metropolitan Institute of Medical Science, Tokyo Metropolitan Organization for Medical Research, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan
Chris Lauber
Department of Medical Microbiology, Leiden University Medical Center, Postzone E4-P, P.O. Box 9600, NL-2300 RC Leiden, The Netherlands
Stanley M. Lemon
Division of Infectious Diseases, Department of Medicine, and the Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295
Hazel Levy
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115
Howard L. Lipton
Department of Microbiology & Immunology, MC790, University of Illinois at Chicago, 835 South Wolcott Avenue, Chicago, IL 60612-7344
Richard E. Lloyd
Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030
Encarna Martínez-Salas
Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Nicolás Cabrera 1, Cantoblanco, Madrid 28049, Spain
Thomas Michiels
de Duve Institute, Université Catholique de Louvain, 74 avenue Hippocrate, B-1200 Brussels, Belgium
Philip D. Minor
Division of Virology, National Institute for Biological Standards and Control (NIBSC), Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, United Kingdom
Steffen Mueller
Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794
David Neubauer
Max F. Perutz Laboratories, Medical University of Vienna, Dr. Bohr-Gasse 9/3, A-1030 Vienna, Austria
Johan Neyts
Rega Institute, Minderbroedersstraat 10, B-3000 Leuven, Belgium
Akio Nomoto
Institute of Microbial Chemistry, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021, Japan
Ann Palmenberg
Institute for Molecular Virology, University of Wisconsin—Madison, 1525 Linden Drive, Madison, WI 53706
Nogi Park
Department of Basic Medical Sciences, University of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, AZ 85004
Aniko V. Paul
Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794
Celia Perales
Centro de Biología Molecular Severo Ochoa, CSIC-UAM, C/Nicolás Cabrera 1, Cantoblanco, Universidad Autónoma de Madrid, Madrid 28049, Spain
Rosa M. Pintó
Department of Microbiology, University of Barcelona, Av. Diagonal 645, Barcelona 08028, Spain
Vincent R. Racaniello
Department of Microbiology & Immunology, Columbia University College of Physicians & Surgeons, Room 1310B, 701 W. 168th Street, New York, NY 10032
Luis L. Rodriguez
Plum Island Animal Disease Center, North Atlantic Area, Agricultural Research Service, U.S. Department of Agriculture, P.O. Box 848, Greenport, NY 11944
Raymond P. Roos
Department of Neurology/MC2030, The University of Chicago Medical Center, 5841 S. Maryland Ave., Chicago, IL 60637
David J. Rowlands
Institute for Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom
Janet M. Rozovics
Department of Microbiology and Molecular Genetics, School of Medicine, Medical Sciences I, B214, University of California, Irvine, Irvine, CA 92697-4025
Martin D. Ryan
Centre for Biomolecular Sciences, University of St. Andrews, North Haugh, St. Andrews, Fife, Scotland, KY16 9ST, United Kingdom
Bert L. Semler
Department of Microbiology and Molecular Genetics, School of Medicine, Medical Sciences I, B237, University of California, Irvine, CA 92697-4025
Peter Simmonds
Centre for Infectious Diseases, University of Edinburgh, Summerhall, Edinburgh EH9 1QH, United Kingdom
Tim Skern
Max F. Perutz Laboratories, Medical University of Vienna, Dr. Bohr-Gasse 9/3, A-1030 Vienna, Austria
Glyn Stanway
Department of Biological Sciences, University of Essex, Wivenhoe Park, Colchester, Essex C04 3SQ, United Kingdom
David I. Stuart
Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford OX3 7BN, United Kingdom
Steven Tracy
Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68195-6495
Frank van Kuppeveld
Department of Medical Microbiology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, P.O. Box 9101 (internal post 268), 6500 HB Nijmegen, The Netherlands
Nuria Verdaguer
Institut de Biología Molecular de Barcelona, Parc Científic de Barcelona, Baldiri i Reixac 10, 08028 Barcelona, Spain
Marco Vignuzzi
Viral Populations and Pathogenesis, Institut Pasteur, 75724 Paris cedex 15, France
J. Lindsay Whitton
Department of Immunology and Microbial Science, SP30-2110, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037
Eckard Wimmer
Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794
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The Picornaviruses pdf epub mobi txt 电子书 下载 2024