Building upon the success of the "Handbook of Laboratory Animal Science" and completing Volumes I and II of the second edition, "Handbook of Laboratory Animal Science, Second Edition: Animal Models, Volume III" provides the final component to present a comprehensive overview of animal models in biomedical research. As with Volume II, this new volume addresses the development and application of models in different areas of biomedical research and details the criteria used to choose animal species and strains. The individual chapters focus on the use of laboratory animals as models for humans in a range of research disciplines, such as for the study of diseases of the different organ systems, for infectious diseases, and for human behavior.Each chapter can be read as a stand-alone text, although the entire handbook is an integrated work that provides an in-depth and extensive introduction to laboratory animal science. With contributions from eminent scientists who share their knowledge and hands-on expertise from their own research, Volume III explains the many factors in choosing animal models and also probes the question of extrapolation of data to humans. It is a critical resource for veterinary and biomedical researchers, laboratory managers and administrators, and other laboratory animal professionals.