The Drug Hunters pdf epub mobi txt 电子书 下载 2025
Dr. Donald R. Kirsch has been a drug hunter for thirty five years, holds twenty-four drug-related patents, has written more than fifty papers, has been a reviewer for prestigious journals, a director, research group leader, and chief science officer at Wyeth, Cyanamid, Squibb, and Cambria Pharmaceuticals, and currently teaches drug discovery at Harvard Extension School. He lives in Bedford, MA.
Ogi Ogas, PhD, is a professional science writer. He is the coauthor of A Billion Wicked Thoughts and Shrinks and has published articles in the Wall Street Journal, Boston Globe, Wired, Glamour, Seed, and Psychology Today. He lives in Boston, MA.
- 药物
- 经济,政治和历史
- 科普
- 科学和心理学
- 制药
- Medical
The surprising, behind-the-scenes story of how our medicines are discovered, told by a veteran drug hunter.
The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity— by chewing, brewing, and snorting—some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the five-thousand-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze-age medicine, a worm-killing birch fungus, knotted to his leggings. Nowadays, Big Pharma conglomerates spend billions of dollars on state-of the art laboratories staffed by PhDs to discover blockbuster drugs. Yet, despite our best efforts to engineer cures, luck, trial-and-error, risk, and ingenuity are still fundamental to medical discovery.
The Drug Hunters is a colorful, fact-filled narrative history of the search for new medicines from our Neolithic forebears to the professionals of today, and from quinine and aspirin to Viagra, Prozac, and Lipitor. The chapters offer a lively tour of how new drugs are actually found, the discovery strategies, the mistakes, and the rare successes. Dr. Donald R. Kirsch infuses the book with his own expertise and experiences from thirty-five years of drug hunting, whether searching for life-saving molecules in mudflats by Chesapeake Bay or as a chief science officer and research group leader at major pharmaceutical companies.
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对于我这种门外汉非常好的普及读物，撇开技术细节谈研究思路。作者回顾了人类千年发现/发明新药的历史：首先是植物时代，直接服用天然植物而不加考虑有效成分，代表是鸦片和金鸡纳霜；第二是19世纪中叶开始的工业化制药时代，大规模标准化生产已证明有药用效果的化学试剂，代表...
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很有意思的书，非常浅显好读。作为前化工工程师，能深刻体会drug hunter们的艰辛，而成药上市的难度对比化工品的研发又是云泥之别了。运气确实比智慧更重要。
评分很有意思的书，非常浅显好读。作为前化工工程师，能深刻体会drug hunter们的艰辛，而成药上市的难度对比化工品的研发又是云泥之别了。运气确实比智慧更重要。
评分很有意思的书，非常浅显好读。作为前化工工程师，能深刻体会drug hunter们的艰辛，而成药上市的难度对比化工品的研发又是云泥之别了。运气确实比智慧更重要。
评分很有意思的书，非常浅显好读。作为前化工工程师，能深刻体会drug hunter们的艰辛，而成药上市的难度对比化工品的研发又是云泥之别了。运气确实比智慧更重要。
评分很有意思的书，非常浅显好读。作为前化工工程师，能深刻体会drug hunter们的艰辛，而成药上市的难度对比化工品的研发又是云泥之别了。运气确实比智慧更重要。
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