Miranda is a bright, attractive woman with an important government job, a nice home, and a prominent lawyer husband. Her fraternal twin sister, Jessica, is a sportswriter who has spent years sacrificing her social life and conventional career prospects to establish a magazine. Jessica's publication has finally caught on after she receives renown for an article she writes about local baseball star Manny Chavez and his perilous journey back to his native Cuba to retrieve his abducted son. Jessica, now engaged to Manny, invites Miranda, her husband, and their parents to join her in a luxury suite to watch the hometown Washington Filibusters take on their archrivals, the Florida Keys, in a championship game. As they are wined and dined by the team owner, Miranda envies her sister's seemingly perfect life and faces the reality that her own is a facade. But when the forces of revenge and corporate greed catch up to the "perfect" couple and blow their world apart, Miranda is suddenly thrust into a world of international politics. Let's Play Ball dramatizes the struggles of two ambitious sisters against the backdrops of immigration, global conflict, and the nation's pastime.