In her novel Illa (1980) Cixous restructures the story of Persephone and Demeter. The Greek goddess Persephone, according to legend, was the daughter of Zeus and Demeter (the Roman goddess Ceres, goddess of crops and fertility). She was abducted and raped by Hades and forced to be his wife. Demeter searched for Persephone and, grieving over her disappearance, decided that the land would be infertile until she was reunited with her daughter. Zeus brokered a deal that would allow Persephone to reside with her mother for two-thirds of the year; for the other third she would be imprisoned in Hell with Hades. Greek mythology uses this myth to explain the earth's barren condition during the winter months. In Illa, Cixous highlights the male-dominated, colonizing aspects of this tale and changes the story to reflect a more self-determined, feminist text. In Illa, she celebrates camaraderie among women, underscores women's link with nature, and highlights the feminine goals of love and nonviolence.

A major figure in contemporary feminist critical theory, Cixous is known for works that analyze and attempt to counter Western culture's traditional concepts of male and female. Cixous is best known for her essay collaboration with Catherine Clément, La jeune née (1975; The Newly Born Woman) and her essay "Le rire de la Méduse" (1975; "The Laugh of the Medusa"). Both texts are recognized as being markedly influenced by the writings of Jacques Derrida, the French philosopher and founder of the critical method known as deconstructionism; Michel Foucault, the French philosopher and historian who rejected the theory of human nature and was a proponent of the notion of an ever-changing self; Jacques Lacan, the French psychoanalyst and philosopher who proposed a linguistic theory of the unconscious; and Sigmund Freud, the originator of psychoanalysis. A proponent of écriture féminine, or feminine writing, Cixous strives in all of her works to establish a uniquely feminine perspective, both to correct what she and many feminist theorists view as the traditionally masculine character of Western discourse and as a methodology with which to critique that discourse.