What is it that turns a new observation into a true scientific discovery? And who may claim the credit? Theoreticians of science, the foremost thinkers of their times among them, have tried to answer these fundamental questions about the nature of scientific progress and discovery.

With clear insight and the chemical as well as philosophical wisdom gained from over fifty years as a practising chemist, Jerome Berson puts their theories to the test. The development of chemistry into a "modern" science during the last two centuries provides him with ample cases to illustrate the way scientific progress really happens.

Kekul?'s struggle to arrive at a structure for benzene, the paradigm change that was necessary to accept the reality of molecular rearrangements, and other episodes are retold here from the philosopher's as well as from the practitioner's perspective, shedding light on the way scientists think and act.

Berson's account of the rather unphilosophical way in which scientific discoveries are made includes the realization that even a false hypothesis, such as Woodward's ideas about the biosynthesis of strychnine, may help rather than hinder scientific progress.

Scientists of all ages, as well as many non-scientists, will find this a highly readable and unusual book.