Clinical Epidemiology

Clinical Epidemiology pdf epub mobi txt 电子书 下载 2026

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出版者:
作者:Grobbee, Diedrerick E., M.D., Ph.D./ Hoes, Arno W., M.D., Ph.D.
出品人:
页数:413
译者:
出版时间:2008-3
价格:$ 143.45
装帧:
isbn号码:9780763753153
丛书系列:
图书标签:
  • 临床流行病学
  • 流行病学
  • 医学统计
  • 循证医学
  • 研究方法
  • 健康科学
  • 公共卫生
  • 临床研究
  • 疾病风险
  • 诊断
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具体描述

New Edition Available 7/1/2013 In the current era of evidence-based medicine, clinical epidemiology is increasingly recognized as an essential tool in the critical appraisal of available evidence and the design of new studies. Clinical Epidemiology: Principles, Methods, and Applications for Clinical Research is a comprehensive resource that introduces the reader to the basics of clinical epidemiology and explores the principles and methods that can be used to obtain quantitative evidence on the effects of interventions and on the diagnosis, etiology, and prognosis of disease. The everyday challenges of clinical research and the quantitative knowledge required to practice medicine are also examined, making this book a valuable reference for both graduate and undergraduate students in medicine and related disciplines, as well as for professionals involved in the design and conduct of clinical research. Key features: * Worked-out examples from daily clinical practice included in all sections. * Relevant clinical research that can be used as exercises. * Several chapters devoted to research assessing the main and adverse effects of interventions, including introductions to clinical trials. * Common study designs (such as meta-analyses, case-control studies and randomized trials), as well as elementary data-analytical issues. Principles and Methods of Clinical Epidemiology explores the challenges clinicians face in daily practice and the quantitative knowledge required to practice medicine. An important distinction is made between research directed at unraveling causality (notably etiologic research and studies addressing the effects of interventions) and descriptive research aimed at predicting the presence (diagnostic research) or consequences of disease (prognostic research). The book is intended for both the users of clinical research findings (i.e. those practicing medicine and related disciplines such as pharmacy, health sciences, nursing sciences, and veterinary medicine) and those involved in the design and conduct of applied clinical research. Also future "users" and "do-ers" of applied clinical research (notably undergraduate students and PhD fellows in medicine and related disciplines) will benefit from the book. Teachers of clinical epidemiology will find the book a valuable reference with their classes.

《Clinical Epidemiology》是一本全面而深入的学术著作,系统地介绍了临床流行病学领域的重要概念、理论和方法。这本书以严谨的研究方法和丰富的实例为基础,帮助读者全面理解该学科的核心内容。内容涵盖从数据收集与分析到研究设计、统计方法及其实际应用的各个环节,旨在为初学者提供坚实的理论基础,同时也为有经验的专业人士更新知识储备。 书中首先系统地讲解了流行病学的基本原理和核心概念,详细介绍了如何设计研究以评估疾病发生、分布及其影响。这部分内容不仅涵盖传统的研究方法,还结合现代数据科学技术,对新兴的统计分析工具进行深入探讨。此外,该书还特别强调了数据质量的重要性,通过实际案例说明如何识别和解决数据中的偏差与限制,确保研究结果的可靠性。 在研究设计部分,书中详细解析了常见实验设计如随机对照试验、观察性研究以及干预研究的具体步骤和注意事项。读者可以通过这些内容了解如何选择合适的设计,避免常见的方法学误区,并提升研究的科学性与有效性。 书中还深入探讨了统计分析在流行病学中的应用,包括描述性统计、假设检验、回归分析等技术手段。这些部分不仅帮助读者掌握基本的数据处理技能,还引导他们理解这些方法如何支持疾病发生率的比较、风险因子的识别以及预测模型的构建。 另一重要内容是对流行病学数据源与工具的介绍,包括流行病学软件使用指南和文献检索技巧。这为读者提供了实用的资源,帮助他们在实际工作中高效地获取并分析必要的信息。书中还特别强调了伦理考量的重要性,在研究设计、数据使用及成果发布环节,详细讨论了如何遵循科研诚信原则。 此外,该书还包括大量案例和实例,通过真实世界的场景,让读者能够更直观地理解理论知识的实际应用。这些案例涵盖不同地区、不同疾病类型以及各种研究方法,帮助读者在思考复杂问题时提供清晰的参考框架。 总的来说,这本书不仅是一份内容丰富的学术指南,更是一个全面指导读者从理论到实践的学习工具。它为希望深入研究或应用流行病学知识的专业人士提供了宝贵的资源,帮助他们建立科学思维、提升分析能力,并在各个层面上做出更具影响力的研究和决策。该书的结构清晰,内容详实,使其成为临床流行病学领域中不可或缺的一部分。

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