In this biological thriller of the near future, postinsurrection Mexico has undermined the superpower of the United States. But while the rivals battle over borders, a pestilence beyond politics threatens to explode into a worldwide epidemic. . . .

Since the rise of the Holy Renaissance, Ascension—once known as Mexico City—has become the most populous city in the world, its citizens linked to a central government net through wetware implanted in their brains. But while their dictator grows fat with success, the masses are captivated by Sister Domenica, an insurgent nun whose weekly pirate broadcasts prophesy a wave of death. All too soon, Domenica’s nightmarish prediction proves true, and Ascension’s hospitals are overrun with victims of a deadly fever. As the rampant plague kills too quickly to be contained, Mexico smuggles its last hope over the violently contested border. . . .

Henry David Stark is a crack virus hunter for the American Center for Disease Control and a veteran of global humanitarian efforts. But this disease is unlike any he’s seen before—and there seems to be no way to cure or control it. Racing against time, Stark battles corruption to uncover a horrifying truth: this is no ordinary outbreak but a deliberately unleashed man-made virus . . . and the killer is someone Stark knows.