Enantioselective Synthesis of Beta-amino Acids pdf epub mobi txt 电子书下载 2026

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出版者:John Wiley & Sons Inc

作者:Juaristi, Eusebio (EDT)/ Soloshonok, V. A. (EDT)

出品人:

页数:634

译者:

出版时间:2005-4

价格:1412.00 元

装帧:HRD

isbn号码:9780471467380

丛书系列:

图书标签:

β-氨基酸
不对称合成
手性合成
有机合成
催化
氨基酸化学
药物合成
合成方法学
立体选择性
有机催化

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具体描述

This book covers all facets of the synthesis of beta amino acids. As evidenced by an exponential increase in the literature published on the subject, interest in beta amino acids has grown over the past several years. With major pharmaceutical applications, these amino acids are now studied across multiple lines of research, including combinatorial chemistry, medicinal chemistry, molecular design, proteomics, and others. This Second Edition of "Enantioselective Synthesis of beta Amino Acids" updates reviews included in the First Edition while also covering new developments since its publication. The book presents detailed discussions of the most important methods for the synthesis of beta amino acids. In most cases, the lead chemist who originally developed a method provides an authoritative description of it. In addition, "Enantioselective Synthesis of beta Amino Acids, Second Edition": features introductory overviews on the structural types of relevant beta amino acid targets and salient beta amino acids present in natural products; dedicates several chapters to advances in the synthesis of oligomers from beta amino acids; includes general and practical procedures for the preparation of beta amino acids in each chapter; discusses the most important methods that have been recently developed for the asymmetric synthesis of cyclic and open chain beta amino acids; includes a report on the preparation of libraries of enantiopure beta amino acids using combinatorial approaches. The only book of its kind available today, "Enantioselective Synthesis of beta Amino Acids, Second Edition" offers upper level students and professionals an essential resource for pharmaceutical development, medicinal chemistry, and biochemistry.

这本书深入探讨了β-氨基酸的合成过程，特别关注了高选择性反应的设计与应用。它系统介绍了不同类型的催化剂及其在生物化学转化中的作用，从酶学原理到现代有机合成方法均进行全面剖析。书中详细描述了一系列实验技术和分析手段，帮助研究者能够精准控制反应条件，从而提高目标产物的纯度与产量。同时，内容涵盖了当前研究热点，如新型催化剂开发、绿色合成路径以及工业应用中的优化策略。这本书不仅适合有化学或生物学背景的专业读者，还为初学者提供了一个系统化的学习框架，使其能够深入理解复杂反应机制。通过丰富的案例研究和图示说明，读者可以直观掌握不同合成路径的优势与挑战。在书中对最新科学成果的总结，使内容始终紧跟行业前沿。无论是从理论知识还是实际操作技巧方面，这本书都提供了极具价值的参考资料。整个结构设计严谨，逻辑清晰，旨在为读者建立全面、系统的化学合成知识体系。这一书不仅关注反应机制，还强调实验设计与问题解决能力的培养，为科研人员和相关学科从业者提供有力的支持。该书内容注重科学性与实用性，综合考虑了学术研究与工业应用的需求，旨在帮助读者全面提升对β-氨基酸合成技术的理解，并为未来的创新提供坚实基础。通过详细描述各阶段反应过程和优化方法，这本书将成为探索有机化学新路径的重要参考。这一作品不仅涵盖了丰富的知识点，更注重实践指导，使每一章都具有实际应用价值，力求满足不同层次读者的需求。