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Toxicokinetics and Risk Assessment pdf epub mobi txt 电子书下载 2024

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Ohanian, Edward V. (EDT)/ Ohanian, Edward V.

Taylor & Francis

2006-10

361

$ 203.34

HRD

9780849337222

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发表于2024-06-24

Toxicokinetics and Risk Assessment epub 下载 mobi 下载 pdf 下载 txt 电子书下载 2024

Toxicokinetics and Risk Assessment pdf epub mobi txt 电子书下载 2024

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Toxicokinetics in Risk Assessment discusses the noncancer risk assessment process and its reliance on uncertainty factors in order to facilitate the continued study and refinement of the scientific basis for health risk assessment. This text clearly demonstrates the application of physiologically-based pharmacokinetic (PBPK) modeling in human health risk assessment, as well as methods for data generation, extrapolation, and inclusion of laboratory results for chemical metabolism and computer-based predictions of biochemical constants to address estimates of variability between experimental animals and humans. This guide also includes recent examples of the use of toxicokinetic information to successfully replace default values for uncertainty factors with data-derived factors in risk assessments developed by the US Environmental Protection Agency.

Toxicokinetics and Risk Assessment 下载 mobi epub pdf txt 电子书